When epilepsy is diagnosed, it is important to try to control the seizures and the social consequences of the disease over several months both in childhood and later in life.

Although difficult to measure, these consequences can be assessed through a set of simple questions.  First and foremost: What course of action to take? Should the focus be controlling the seizures, remission with or without anti-epileptic medication, quality of life or a combination of all of the above? Secondly, why try to predict outcomes and who will use this information? Thirdly, exactly how precise are these predictions?

Based on the conclusions of a workshop bringing together 49 international experts, the aim of this book is to take a critical look at our current knowledge of epilepsy outcomes in children and identify clinical and basic research pathways for the future.


  • Entrance criteria and outcome measures in pediatric epilepsy clinical trials
  • Is it possible to predict the outcome of childhood epilepsy?
  • Prognostic factors for recurrence after a first unprovoked seizure in childhood
  • Newly diagnosed epilepsies: clinically relevant conclusions from global studies on outcome
  • Does treatment with antiepileptic drugs influence the long-term outcome of newly diagnosed epilepsies?
  • The influence of convulsive status epilepticus on outcomes of childhood epilepsy
  • Mortality in children with epilepsy
  • Immune-related mechanisms of seizures: insights from experimental models
  • Febrile infection-related epilepsy syndrome (FIRES): pathogenesis, treatment, and outcome - a large cohort and update
  • Are idiopathic epilepsy syndromes in neonates always "benign?"
  • Neonatal epilepsy and underlying aetiology (other than idiopathic): to what extent do the seizures and the EEG abnormalities influence outcome?
  • Infantile spasms: what matters more? Seizures, EEG, underlying aetiology, or treatment?
  • Lennox-Gastaut syndrome: nosographic limits and long term outcome
  • Dravet syndrome - What matters more: seizures or the underlying aetiology?
  • Epileptic encephalopathy with continuous spike-waves during slow-wave sleep including Landau-Kleffner syndrome: what determines the outcome?
  • Outcome of idiopathic generalized epilepsy and the role of EEG discharges
  • Refractory childhood epilepsy: comparing the outcome of medical versus surgical treatment
  • Adult outcome of childhood-onset, cause unknown (cryptogenic), MRI-negative, focal epilepsy
  • Focal non-idiopathic epilepsies: does outcome after epilepsy surgery depend on the localization of the epileptogenic zone in frontal and temporal lobe epilepsy?
  • Outcome after epilepsy surgery of MRI-negative non-idiopathic focal epilepsies
  • Outcome when malformations of cortical development (MCD) are the cause
  • Timing of antiepileptic drug withdrawal after pediatric epilepsy surgery
  • Anxiety and depression in children with epilepsy
  • Health perception and socio-economic status of childhood onset epilepsy
  • What if quality of life better expressed outcomes for epilepsy?


Editeur : John Libbey

Auteur(s) : Willem F. Arts, Alexis Arzimanoglou, Oebele Brouwer, Carol Camfield, Peter Camfield

Collection : Progress in Epileptic Disorders

Publication : 3 juin 2013

Edition : 1ère édition

Intérieur : Noir & blanc

Support(s) : Text (eye-readable) [PDF + ePub]

Contenu(s) : PDF, ePub

Protection(s) : Marquage social (PDF), Marquage social (ePub)

Taille(s) : 4,4 Mo (PDF), 2,1 Mo (ePub)

Langue(s) : Anglais

Code(s) CLIL : 3165

EAN13 Text (eye-readable) [PDF + ePub] : 9782742011957

EAN13 (papier) : 9782742011025

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