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Generalized Seizures: From clinical phenomenology to underlying systems and networks

de Edouard Hirsch (auteur), Frederick Andermann (auteur), Patrick Chauvel (auteur), Jerome Engel (auteur), Fernando Lopes da Silva (auteur), Hans O. Lüders (auteur)
Maison d'édition : John Libbey
Collection : Progress in Epileptic Disorders
septembre 2006
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Résumé

A "Generalized seizure" corresponds to an ictal manifestation whose initial semeiology indicates, or is consistent with, more than minimal involvement of both cerebral hemispheres. A network is a functionally and anatomically connected set of cortical and subcortical brain regions in which activity in any one part affects activity in all others. A system is a group of independent but interrelated elements (networks) comprising a unified whole. A considerable amount of evidence supports the existence of specific cortical and subcortical networks in the genesis, expression and control of generalized seizures. Animal and human data suggested that the so-called generalized seizures involve selective networks while sparing others. A greater understanding of those systems and networks, thoroughly debated in this book, will ultimately lead to improved targeted therapies for so-called generalized epilepsies.

Sommaire

  • Foreword
  • Workshop participants
  • Generalized seizures and epilepsies: a bilateral "focal" dysfunction?
  • Tonic seizures and brainstem systems
  • Absence seizures and cortico-thalamic systems
  • Myoclonic seizures and the frontal lobe
  • Primary versus Secondary Tonic-clonic seizures
  • The "cortical" and "centrencephalic" theories revisited
  • Phenomenology versus networks: clinical consequences
  • Concluding remarks

Caractéristiques

Editeur : John Libbey

Auteur(s) : Edouard Hirsch, Frederick Andermann, Patrick Chauvel, Jerome Engel, Fernando Lopes da Silva, Hans O. Lüders

Collection : Progress in Epileptic Disorders

Publication : 28 septembre 2006

Edition : 1ère édition

Intérieur : Noir & blanc

Support(s) : Text (eye-readable) [PDF]

Contenu(s) : PDF

Protection(s) : Marquage social (PDF)

Taille(s) : 3,8 Mo (PDF)

Langue(s) : Anglais

Code(s) CLIL : 3165

EAN13 Text (eye-readable) [PDF] : 9782742008810

EAN13 (papier) : 9782742006212

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